Os poderes místicos das tartarugas ninja são colocados à prova quando criaturas impiedosas de outro universo tentam instaurar o caos.
Leo / Janitor Man (voice)
Raph / Office Man 1 (voice)
Mikey / Foot Soldier 1 (voice)
Donnie / Security AI / Tank AI / Dragged Man (voice)
Casey Jones / Foot Soldier 3 (voice)
Splinter / Additional Characters (voice)
April O'Neil / Café Woman 3 (voice)
Krang One / Military Soldier 1 (voice)
Krang Two / Military Woman (voice)
Hypno-Potamus (voice)
Diretor